Spravato Nasal Spray
If you are struggling with depression and have tried two or more antidepressants* in your current episode without adequate relief, talk to the professionals at Certus to see if you have treatment-resistant depression.
In a clinical study of adults with treatment-resistant depression, those who took Spravato and an oral antidepressant experienced greater reductions of depression symptoms at four weeks compared to those who received a placebo plus an oral antidepressant.†
†Based on an overall score on a standardized rating scale.
Spravato can only be administered at Certus. As a certified Spravato™ treatment center, we are one of the few practices in the Triad that is authorized to administer this medication.
What to expect. Spravato™ is inhaled in a preset dose. You must remain in our office for up to two-hours for observation after the prescription is administered. You will require transportation to and from our offices. You’ll take SPRAVATO™ twice a week for the first month. During the second month, you’ll take it once a week. After that, you’ll take it once a week or once every two weeks. You’ll continue to take an oral antidepressant as prescribed. Click here to learn more.
What You Need to Know about Spravato™
Spravato™ can cause serious side effects, including:
- Sedation and dissociation. Spravato™ may cause sleepiness (sedation), fainting, dizziness, spinning sensation, anxiety, or feeling disconnected from yourself, your thoughts, feelings, space and time (dissociation).
- A Certus care provided must monitor you for serious side effects for at least 2 hours after taking Spravato™. We will decide when you are ready to leave the healthcare setting.
- Abuse and misuse. There is a risk for abuse and physical and psychological dependence with Spravato™ treatment. We will check you for signs of abuse and dependence before and during treatment with Spravato™.
- Tell us if you have ever abused or been dependent on alcohol, prescription medicines, or street drugs. We can tell you more about the differences between physical and psychological dependence and drug addiction.
- Increased risk of suicidal thoughts or actions. Spravato™ may cause worsening of depression and suicidal thoughts and behaviors, especially during the first few months of treatment and when the dose is changed. Depression and other serious mental illnesses are the most important causes of suicidal thoughts and actions. Some people may have a higher risk of having suicidal thoughts or actions. These include people who have (or have a family history of) depression or a history of suicidal thoughts or actions.
How can I watch for and try to prevent suicidal thoughts and actions?
- Pay close attention to any changes, especially sudden changes, in mood, behavior, thoughts, or feelings, or if you develop suicidal thoughts or actions. Tell your healthcare provider right away if you have any new or sudden changes in mood, behavior, thoughts, or feelings.
- Keep all follow-up visits with your healthcare provider as scheduled. Call your healthcare provider between visits as needed, especially if you have concerns about symptoms.
- Tell your healthcare provider right away if you have any of the following symptoms, especially if they are new, worse, or worry you:
- attempt to commit suicide
- thoughts about suicide or dying
- worsening depression
- other unusual changes in behavior or mood